Margaret Caplette-Tanner was last seen on the 900 block of Elphinstone Street on April 7, at about 4:00 p.m.
She is described as Aboriginal, 100 pounds with an athletic build, brown eyes and black shoulder length hair. Caplette-Tanner was last seen wearing a black hooded sweater, blue jeans and white runners.
Police say there is no reason to believe Caplette-Tanner has come to any harm, but she is vunerable because of her age and police need to locate her to ensure she is safe.
Anyone with information is asked to contact the Regina Police Service at 306-777-6500 or Crime Stoppers at 1-800-222-8477.